Cross-limb communication during Xenopus hind-limb regenerative response: non-local bioelectric injury signals
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چکیده
منابع مشابه
On regenerative and collateral sprouting to hind limb digits after sciatic nerve injury in the rat.
PURPOSE This study examines the proportions of regenerative and collateral sprouting to the skin after peripheral nerve injury. METHODS In the first experimental paradigm, primary afferent neurones were pre-labelled with Diamidino Yellow (DY), injected in digit 3, followed by sciatic nerve section and repair. After three months of regeneration, digit 3 was re-injected with Fast Blue (FB) to l...
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To clarify the mechanism of limb regeneration that differs between mammals (non-regenerative) and amphibians (regenerative), responses to limb amputation and the accessory limb inducible surgery (accessory limb model, ALM) were compared between mice and Xenopus, focusing on the events leading to blastema formation. In both animals, cartilaginous calluses were formed around the cut edge of bones...
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Background: Management of lymphedema is a challenging issue in surgery. A variety of operations have been used, albeit with little success. Objective: To investigate the efficacy of testicular patch as a lymphatic conduit. Methods: An incision was made on the inguinal area of 10 dogs and all lymph nodes of inguinal area were excised. The tunica albuginea and parenchyma near the hilum of testes...
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In vivo animal model systems, and in particular mouse models, have evolved into powerful and versatile scientific tools indispensable to basic and translational research in the field of transplantation medicine. A vast array of reagents is available exclusively in this setting, including mono- and polyclonal antibodies for both diagnostic and interventional applications. In addition, a vast num...
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Composite tissue allotransplantation (CTA) now represents a valid therapeutic option after the loss of a hand, forearm or digits and has become a novel therapeutic entity in reconstructive surgery. However, long term high-dose multi-drug immunosuppressive therapy is required to ensure graft survival, bearing the risk of serious side effects which halters broader application. Further progression...
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ژورنال
عنوان ژورنال: Development
سال: 2018
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.164210